Is IBS An Autoimmune Disease?

Irritable Bowel Syndrome (IBS) is a disorder of the digestive system that is characterized by a range of symptoms including abdominal pain bloating diarrhea constipation. Although the exact cause of IBS remains unknown there have been various theories regarding its development. One theory is that IBS may be an autoimmune disease.

What is an Autoimmune Disease?

Autoimmune diseases are disorders that occur when the immune system attacks destroys healthy cells in the body. In normal circumstances the immune system identifies attacks foreign cells that are harmful to the body. However in cases of autoimmune diseases the immune system mistakenly identifies healthy cells in the body as foreign cells. The immune system attacks destroys these cells leading to tissue damage inflammation.

The Link Between IBS Autoimmune Disease

While there is still no concrete evidence proving that IBS is an autoimmune disease there is growing evidence suggesting a possible connection between the two. One study published in the Journal of Gastroenterology Hepatology found that people with IBS were more likely to have autoimmune diseases such as celiac disease rheumatoid arthritis systemic lupus erythematosus.

Another study published in the Journal of Neurogastroenterology Motility suggests that IBS may result from an immune system dysfunction known as “low-grade inflammation.” This dysfunction is characterized by increased levels of inflammatory cells in the gut. As a result the immune system mistakenly attacks healthy cells in the gut leading to the development of IBS.

Conclusion

Despite these studies IBS is not considered to be a full-fledged autoimmune disease. There is still much research to be done in order to confirm whether IBS is indeed an autoimmune disease. However understanding the possible connection between IBS autoimmune diseases may help in developing new treatments for IBS sufferers. Until more is known the best approach is to work with your doctor to manage your IBS symptoms through lifestyle changes dietary changes medication when necessary.